Thursday, 1 August 2013

Therapy for Severe Vasculitis Shows Long-Term Effectiveness

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Therapy for Severe Vasculitis Shows Long-Term Effectiveness

Results from an NIAID-supported clinical trial show that administering the drug rituximab once weekly for one month provides the same benefits as 18 months of daily immunosuppressive therapy in people with severe forms of vasculitis. Rituximab’s shorter treatment duration may decrease the risk of long-term side effects of immunosuppression, such as cancer, infertility, and infection.

The trial tested rituximab’s safety and effectiveness in 197 participants with the rare autoimmune diseases granulomatosis with polyangiitis, formerly known as Wegener’s granulomatosis, and microscopic polyangiitis. The researchers describe their results in the August 1 issue of the New England Journal of Medicine.

Read more about the study.


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